One of Japan’s most venerable and oldest animation studios is the legendary Madhouse. This company is responsible for some of the most daring off-beat anime which, while deviating from the usual formula, still manage to set its own trends. Madhouse chooses its adaptations well and pours its hearts and souls into animating them. Thebest Madhouse animeare also some of the industry’s greatest series and movies of all time.
Beyond its impressive choice ofmanga or projects to adapt into films or shows, Madhouse is also famous for its consistent quality. The studio’s anime has always held a reputation for having meticulous attention to detail. Films likePerfect BlueandRedlineperfectly illustrate its animation prowess. Meanwhile, Madhouse’s TV shows also reflect its design philosophies.
Updated June 18, 2025, by Mark Sammut: Madhouse is currently on something of a roll, and the studio has more to show for itself than just Frieren. In fact, Fall 2024 produced one of thebest Madhouse animeever, and this show will continue to air new episodes throughout Winter 2025. Click below to jump to this series.
Madhouse has quite a few isekai anime under its belt, most of which are among the theme’s better efforts.No Game, No Lifeused to be the studio’s most popular dip into these types of stories, but it has arguably become eclipsed byOverlord, which has now produced four seasons and multiple movies. At this point, Ainz and his subordinates are among Madhouse’s most recognizable characters, and they are unlikely to disappear anytime soon.
As adark fantasy twist on the isekai formula,Overlorddelivers fun characters, wicked humor, and a steadily expanding scope that eventually reaches world-conquering levels. As far as OP protagonist shows are concerned, this anime is among the more entertaining; however, its quality can vary quite a bit from season to season. The third entry had a notorious dip in animation that overshadowed a fairly pivotal story beat, undermining what was otherwise a solid season.
Orb: On the Movements of the Earthis such a unique anime. Set in Poland during the 1400s, the story follows different groups of people who are determined to create a truthful model of the universe, a process that involves directly challenging the church’s established doctrine. As this type of research is forbidden, practitioners are generally risking their lives in pursuit of knowledge, and they are well aware that they could find themselves arrested, tortured, and killed.
The setting and premise are already enough to setOrbapart from most other shows, but the anime even takes other storytelling risks. The series runs through a few protagonists, with each person building on the work of their predecessor. Well-written, beautifully animated, and consistently tense, this Fall 2024 is one of the most captivatingMadhouse animeof all time.
Madhouse has a monopoly on gambling anime, producing most of the genre’s best shows.Akagihas an all-time great villain,One Outshas an all-time great protagonist, andDeath Paradehas an all-time great concept; meanwhile,Kaijiis simply thegreatest gambling animeof all time. While not necessarily the most entertaining, in terms of pure tension, this series is completely unchallenged. Dragged into a nightmare thanks to a “friend,” Kaiji finds himself in an underground (or on the ocean) gambling den, desperately engaging in a battle for survival while acting as entertainment for the rich and powerful.
Kaijihas consequences. Although capable of coming up with clever plays, the protagonist is not a genius or infallible, and he can lose at any given moment. No stakes are too high and failure happens, creating an experience that leaves viewers constantly on edge.
Satoshi Kon worked regularly with Madhouse, and the two formed a relationship that regularly produced gold.Paranoia Agentwas the director’s sole TV show, at least as the main creative force behind the core vision. While perhaps not reaching the impossible heights ofPerfect BlueorMillennium Actress, this 2004 psychological thriller nevertheless showcases Kon’s unique and powerful voice.
Tokyo finds itself the victim of a strange crime spree. A boy called Lil' Slugger has been going around smashing people with his bat, an event that changes the latter’s lives in more ways than just physical. Although an overarching plot is present,Paranoia Agentis fairly episodic, with most segments highlighting different characters. As such, the quality of the stories varies quite a bit; however, the best ones (episode 3) are masterpieces.
A classic action series,Black Lagoonis all thrills and very little filler. Split into two seasons and an OVA series, the anime follows a group of merchants as they take on an eclectic range of cases, each one different from the last and most of them being very high quality.
Although largely remembered for its intense action sequences and mature protagonists,Black Lagoonalso throws out the occasional philosophical musings, and they are surprisingly effective and nuanced. Except for season 2’s final arc that threatens to overstay its welcome, the anime barely sets a foot wrong throughout its entire run, delivering top-quality animation every step of the way.
Madhouse has quite a fewgreat sports animeunder its belt, including one of the more unique entries in the genre:One Outs. Despite centering around baseball, the show has more in common with gambling series likeKaijuandAkagi, particularly the latter. The title refers to a street game that pits a pitcher against a batter in 1v1 action, with cash being on the line. Although he does not seem especially talented, Toa Tokuchi has never failed to strike someone out, and that trend continues when he faces off against Saikyou Saitama Lycaons' best batter. Long story short, the Lycaons sign Toa, and he accepts a performance-based contract that is effectively a high-stakes bet with the team’s owner.
One Outsis all about mindgames. In each match, Toa focuses on breaking the psyches of his opponents, a process that is generally quite subtle. While technically the main character, Toa’s thoughts are not revealed to the audience, putting the latter in the same position as the players who are trying to decipher the protagonist’s intentions. This creative decision turnsOne Outsinto a psychological drama, and an intense one at that.
Beckoffers a dramatic spin on the “lost, directionless youth” trope as it sees its protagonist, Yukio Tanaka on a journey of self-realization. He initially had no goals in life (like a lot of young people these days both in and out of Japan). But all that changed after he saved a dog named Beck.
By chance, Beck’s owner happened to be a semi-popular guitarist and member of a budding rock band. Since then, Yukio was introduced to the world of Western rock and was enamored with music. Together with his newfound friends and a shining ambition to make it big worldwide, Yukio will set out to give his viewers a look into how rockers succeed.
One of the sci-fi cult classics of the 1990s,Trigunis about a conflicted banditwho doesn’t actually want to kill people. His name is Vash the Stampede, and he has a dizzyingly huge bounty on his head. The kicker is that he loathes violence due to his troubled past as an experimental weapon; he was manipulated into killing too many innocents for his psyche to handle.
It’s similar in tone to other classics of its era, such asRurouni Kenshin.Heck, both Vash and Kenshin Himura even share the same red motif in their clothing, signifying the guilt and innocent blood stains they’re carrying.Trigunhighlights Madhouse’s fantastic animation along with its deft handling of very-90s comedy.
While not associated withmagical girls, Madhouse’s main contribution happens to be one of the genre’s defining classics.Cardcaptor Sakurasits alongsideSailor Moonas a definitive traditional example of the theme, blending charming characters with clever humor, tasteful romance, and mostly solid action.
As a coming-of-age story, the anime is fantastic, with the original 1998 series and its movie sequels aging surprisingly well. 2018’s sequel,Clear Card, did not quite reach the same heights, but it is a more than acceptable continuation. Admittedly, someone’s mileage with this series will come down to their appreciation for magical girls in general.
14Parasyte -The Maxim
MyAnimeList: 8.33
When it comes to action-oriented anime, Madhouse is no stranger to calling dibs on reluctantly violent protagonists.Parasyte - The Maximis another one of their titles that dabbles with this trope. This time around, the trope involves Shinichi Izumi who was accidentally chosen by Migi, an alien parasite who failed to take over his brain and granted him some nifty but disturbing powers.
Shinichi, being the upstanding member of society he is, decides to use his newfound powers for good all the while wrestling with Migi for control of his body and morals. The two entities slowly begin to influence each other’s personalities as they become a single being.
